Home

Capabilities

Previous Studies

Publications

Abstracts

 

Jobs/Careers

Management Team

Links

Contact Us

 

Map
 
Travel Directions

 

Please click  here to download our brochure.
 

 Medicines Evaluation Unit - Previous Studies - Abstracts

Abstracts/Posters

1. Langley S J, Murdoch R D, Compton C H, Masterson C M, Woodcock A A. Lack of bronchodilatory effect of BRL 55834 (a selective potassium channel activator) in asthmatic patients. Am J Respir Crit Care Med 1996; 153 (4):A804.

2. Langley S J, Masterson C M, Batty E P, Woodcock A. Bronchodilator response to salbutamol after chronic dosing with salmeterol. Am J Respir Crit Care Med 1997; 155 (4):A345.

3. Langley S J, Svanberg C. A study assessing the efficacy of one sodium cromoglycate capsule from Spinhaler vs Eclips in AMP challenge. Allergy 1997; 37:188.

4. Langley S J, Woodcock. Salbutamol dose response after chronic treatment with salmeterol. Eur Respir J 1997; 10 (suppl 25):2s.

5. Jones M, Langley S J. The role of saline as a baseline in histamine challenges. Eur Respir J 1997; 10 (suppl 25):57s.

6. Simpson A, Custovic A, Adisesh A, Pipis S, Hallam C, Craven M, Cain G, Langley S J, Faragher E B, Woodcock A. Exhaled nitric oxide (eNO) in relation to sensitisation and exposure to indoor allergens in asthmatics. American Academy of Allergy and Immunology meeting, Washington February 1998.

7. Langley S J, Masterson C M, Batty E P, Jones M. The subjective sensation of chest tightness during bronchodilation in asthmatics. Am J Respir Crit Care Med 1998; 157/3):A920.

8. Langley S J, Masterson C M., Batty E P, Jones M, Sykes A, Bogolubov M, Stahl E G, Woodcock A. Comparison of single doses of HFA 134A propellant and CFC salbutamol in mild to moderate asthmatic patients. Eur Respir J 1998; 12 (suppl 28):67s.

9. Villeran C, O'Neill S O, Helbling A, Van Noord J A, Lee T, Chuchalin A G, Langley S J, Gunewardena K, Suskovic S, Laurenzi M, Jasan J, Leff J A. Montelukast compared to Salmeterol in the treatment of exercise-induced asthma (EIA). Eur Respir J 1998; 12 (suppl 28):361s.

10. Compton C, Cedar E, Nieman RB, Amit O, Langley S J, Sapene M. Ariflo improves pulmonary function in patients with asthma: results of a study in patients taking inhaled corticosteroids. Am J Respir Crit Car Med 1999; 159/3:A624.

11. Jones M, Langley S J, Masterton C M, Batty E P. Correlation of airways resistance measured using the interrupter technique (MicroRint) with standard spirometry. Am J Respir Crit Car Med 1999; 159/3:A651.

12. Langley S J, Jones M, Williams A J, Batty E P. Assessment of a hand held interrupter device (MicroRint) to measure bronchodilator effects in adult asthmatics. Am J Respir Crit Car Med 1999; 159/3:A652

13. Langley S J, Masterson CM, Batty E P, Jones M. Assessment of a hand held interrupter device (MicroRint) to measure bronchodilator effects in healthy volunteers. Eur Respir J 1999; 13 (suppl ):71s.

14. Brutsche M H, Brutsche I C, Munavvar M, Langley S J, Masterson C, Daley-Yates P T, Brown R, Woodcock A. Pharmacokinetics and systemic effects of inhaled fluticasone propionate (FP) are different in asthmatics (A) and normal volunteers. Eur Respir J 1999; 12 (suppl): 345s.

15. Compton C, Cedar E, Nieman RB, Amit O, Langley S J, Sapene M. SB 207499 improves pulmonary function in patients with asthma receiving inhaled corticosteroids. Eur Respir J 1999; 12 (suppl): 288s.

16. Langley S, Woodcock A, Jones S.W., Rice L. A placebo controlled comparison of single doses of salmeterol and the combination bronchodilator Combivent on lung function over 12 hours in patients with chronic obstructive pulmonary disease (COPD). BMJ 1999; 54 (suppl 3), A65

17. JC. Kips, BJ. O'Connor, SJ. Langley, A. Woodcock, HAM. Kerstjenens, DS Postma, M. Danzig, F. Cuss, RA. Pauwels. Results of a Phase I trial with SCH55700, A humanized anti-IL5 antibody, in severe persistent asthma. Am J Respir Crit Car Med 2000; 16, 161:A505

18. P.T. Daley-Yates, J. Tournant, M.H. Brutsche, I. Carlen-Brutsche, M. Munavar, S. Langley, C. Masterson, A.A. Woodcock. Pulmonary absorption kinetics of fluticasone propionate (FP) in healthy subjects and asthmatics. Am J Respir Crit Car Med 2000,; 16, 161:A774

19. A. Frew, S.J.Langley, E.Gooden. Therapeutic equivalence of inhaled budesonide (100mg bd) delivered by either a new multi-dose dry powder inhaler (Airmax™) or a conventional dry powder inhaler (Turbohaler®) using airways reactivity to inhaled adenosine 5’-monophosphate in asthmatic subjects. ERS, Florence, Aug 2000.

20. P.T. Daley-Yates, J. Tournant, M.H. Brutsche, I. Carlen-Brutsche, M. Munavar, S. Langley, C. Masterson, A.A. Woodcock. Lung residence time and absorption rate for inhaled fluticasone propionate (FP) in healthy subjects and asthmatics. Eur Respir J 2000;16 (suppl 31): 279s.

21. SJ Langley, S Goldthorpe, A Woodcock, A Custovic. Effect of atopy and exposure to indoor allergens on lung function and airway reactivity in asthma. Am J Respir Crit Car Med 2001;163:5:A602

22. S Goldthorpe, SJ Langley, M Craven, A Simpson, A Custovic, A Woodcock. Sensitisation and exposure to indoor allergens increases exhaled nitric oxide in asthma. Am J Respir Crit Car Med 2001;163:5:A720

23. SJ Langley, S Goldthorpe, C Hallam, A Custovic, A Woodcock. Exhaled nitric oxide, bronchial reactivity and pulmonary function in asthma. Am J Respir Crit Car Med 2001;163:5:A421

24. SJ Langley, A Derham, J Holden, C Whale, D Mukherjee, P Hedgland, A Woodcock. Comparison of efficacy of fluticasone HFC 134a metered dose inhaler and fluticasone (dry powder) diskhaler. Am J Respir Crit Car Med 2001;161:5:A441.

25. SD Singh, C Whale, A Hatton, N Houghton, N Raza, PT Daly-Yates, AA Woodcock. Comparison of the pharmacokinetics of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease and healthy subjects. American Journal Of Respiratory & Critical Care Medicine, April 2001:

26. K Wilson, SD Singh, AA Woodcock. An audit of the use of salbutamol in mild asthmatics. American Journal Of Respiratory & Critical Care Medicine, April 2001:

27. C Whale, SD Singh, AA Woodcock. The reproducibility of capsaicin cough in healthy subjects. American Journal Of Respiratory & Critical Care Medicine, April 2001:

28. SD Singh, A Hatton, C Sutton And AA Woodcock. Repeat tuberculin testing at 1 week causes a booster effect in UK subjects. American Journal Of Respiratory & Critical Care Medicine, April 2001.

29. C Whale, SD Singh, N Houghton, A Hatton, AA Woodcock. Salbutamol induced changes in ventilation-perfusion and pulse in chronic obstructive pulmonary disease. American Journal Of Respiratory & Critical Care Medicine, April 2001:

30. J. F. Donohue, J. A. van Noord, S. J. Langley, A. Lee, S. Kesten, L. J. Towse. Superior bronchodilation of once daily tiotropium compared to twice daily salmeterol in patients with COPD. Eur Respir J 2001;18(suppl 33):26s

31. S. J. Langley, S. Goldthorpe, A. Custovic, A. A. Woodcock. Effect of disease duration on pulmonary function in asthma. Eur Respir J 2001;18(suppl 33):34s.

32. S. J. Langley, B. McDonnell, D. Allen, N. Wheeler, M. Briggs, A. A. Woodcock. Effect of fine particle mass (FPM) on the bronchodilator and bronchoprotective properties of salmeterol. Eur Respir J 2001;18(suppl 33):101s

33. S. J. Langley, S. Goldthorpe, A. Custovic, A. Woodcock. Allergen exposure in non-dog and non-house dust mite sensitized atopic asthmatic subjects; effect on bronchial reactivity. Eur Respir J 2001;18(suppl 33):482s.

34. D.J. Allen, K. Wilson, R. Bright-Thomas, B. McDonnell and S.D. Singh. The Pharmacology of Leukotriene D4 Induced Inflammation in Human Skin. British Pharmacology Journal, 2001.

35. S Langley, L Towse, S Kesten, PM Calverley. Heart rate and rhythm analysis from holter monitoring in COPD patients receiving tiotropium. Am J Respir Crit Car Med 2002;165:8:A592

36. C.E. Austin, S.T. Woolley, M. Christie, S. Langley, C. Taylor, A. Young and C.A. Sargent.CXCR1 and CXCR2 expression on leukocytes from normal and COPD patients. Am J Respir Crit Car Med 2002;165:8:A597.

37. Terry Woolley, Carol Weyman-Jones, Stephen Langley, Alan Young and Carol Sargent Systemic levels of IL-1Ra and IL-s1r11 are modulated in stable COPD patients. Am J Respir Crit Car Med 2002;165:8:A597

38. D Acerbi , P Daley Yates , G Poli , A Woodcock , S Langley. Pharmacokinetics of a New CFC-free Metered Dose Inhaler of Beclomethasone Dipropionate Following Multiple Dosing in AsthmaticPatients. Respiratory Drug Delivery VIII, 2002, Vol 2, pp 395-398

39. A.A.Woodcock, I.D.Pavord, L.Rice and T.P.McCarthy. A comparison of the anti-inflammatory and clinical effects of salmeterol/fluticasone propionate combination (SFC) with fluticasone propionate (FP) plus montelukast (M) in patients with mild to moderate asthma. ATS 2003

40. D.J. Allen, R.J. Bright-Thomas, B.M. McDonnell, A. Pankhania, E.P. Batty, S.J. Langley, A. Rossetti and A. Woodcock. A single centre open study into the safety of Pulvinal™, a new dry powder beclomethasone dipropionate (BDP) inhaler in the treatment of mild to severe asthmatics. ATS 2003

41. Stephen J Langley, Elizabeth P Batty, Catherine M Masterson, Luca Cantini, and Ashley Woodcock. Comparison of single doses of salbutamol delivered from a metered dose inhaler (MDI) and a novel dry powder inhaler (DPI) in asthmatic patients. ATS 2003

42. C.M.Houghton, S.D.Singh and A.A Woodcock. Reproducibility of Impulse Oscillometry, Plethysmography and Spirometry in Asthmatic and Healthy Subjects. AmJRCCM ;2003: 167;7 A141.

43. C Houghton, SJ Langley, J Holden, SD Singh, A Rossetti, L Cantini, A Woodcock. Comparison of Formoterol HFA-134a Modulite™, Foradil™ CFC and Foradil™ Aerolizer™ and placebo on the bronchoprotective and bronchodilator effects in a double blind, double dummy, cross-over study. asthma, volume 4, supplement 1, 2003, a38

44. DJ Allen, S Percy, SJ Langley, A Woodcock. Regular inhaled combination therapy provides sustained improvement in lung function in asthmatic adults. World Asthma Meeting, Bangkok, 2004
  

 

5 August 2011

 

 

The MEU is pleased to announce that we are now accredited with the ISO9001:2008 Quality Management Systems award.

 

 

3 June 2011

 

Please visit us at:

 

47th Annual Meeting

DIA 2011 – Convergence of Science, Medicine and Health

19th June to 23rd June 2011

The McCormick Place, Chicago, Illinois

 

 

1 June 2011

 

Work has started on the extension of the Langley Building to provide 36 beds for future clinical trials.

 

7 November 2010

 

Wythenshawe Hospital COPD Day

 

Listen to Maggie Adu, Volunteer Services Advisor, talking about the COPD Day.

 

 

 © Copyright Notice   Developed by the Barsbank Group
 Privacy Policy       Sitemap   Maintained by Amita (UK) Limited